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020 _a9781119970606
_q(electronic bk.)
020 _a1119970601
_q(electronic bk.)
029 1 _aAU@
_b000048489624
029 1 _aNZ1
_b14287073
029 1 _aNZ1
_b15290894
029 1 _aDEBBG
_bBV043393577
035 _a(OCoLC)757486975
_z(OCoLC)754329709
_z(OCoLC)839834452
035 _a(OCoLC)ocn757486975
037 _a10.1002/9781119970606
_bWiley InterScience
_nhttp://www3.interscience.wiley.com
039 9 _a201904121152
_bemilda
_y12-19-2018
_zhafiz
040 _aDG1
_beng
_epn
_cDG1
_dIDEBK
_dYDXCP
_dOCLCQ
_dCOO
_dOCLCQ
_dOCLCA
_dNLGGC
_dOCLCO
_dOCLCQ
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_dEBLCP
049 _aMAIN
050 4 _aQH324.2
_b.H36 2011
082 0 4 _a570.285
_223
245 0 0 _aHandbook of statistical systems biology /
_cedited by Micahel P.H. Stumpf, David J. Balding, Mark Girolami.
264 1 _aChichester :
_bWiley,
_c2011.
300 _a1 online resource (536)
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
504 _aIncludes bibliographical references and index.
505 0 _aMethodological Chapters. Two Challenges of Systems Biology / William S Hlavacek -- Introduction to Statistical Methods for Complex Systems / Tristan Mary-Huard, Sťphane Robin -- Bayesian Inference and Computation / Christian P Robert, Jean-Michel Marin, Judith Rousseau -- Data Integration: Towards Understanding Biological Complexity / David Gomez-Cabrero, Jesper Tegner -- Control Engineering Approaches to Reverse Engineering Biomolecular Networks / Francesco Montefusco, Carlo Cosentino, Declan G Bates -- Algebraic Statistics and Methods in Systems Biology / Carsten Wiuf -- Transcriptomic Technologies and Statistical Data Analysis / Elizabeth Purdom, Sach Mukherjee -- Statistical Data Analysis in Metabolomics / Timothy M D Ebbels, Maria De Iorio -- Imaging and Single-Cell Measurement Technologies / Yu-ichi Ozaki, Shinya Kuroda -- Technology-Based Chapters. Protein Interaction Networks and Their Statistical Analysis / Waqar Ali, Charlotte Deane, Gesine Reinert -- Networks and Graphical Models. Introduction to Graphical Modelling / Marco Scutari, Korbinian Strimmer -- Recovering Genetic Network from Continuous Data with Dynamic Bayesian Networks / Gal︠le Lelandais, Sophie Lb̈re -- Advanced Applications of Bayesian Networks in Systems Biology / Dirk Husmeier, Adriano V Werhli, Marco Grzegorczyk -- Random Graph Models and Their Application to Protein-Protein Interaction Networks / Desmond J Higham, Nata₍a Pr°ulj -- Modelling Biological Networks via Tailored Random Graphs / Anthony C C Coolen, Franca Fraternali, Alessia Annibale, Luis Fernandes, Jens Kleinjung -- Dynamical Systems. Nonlinear Dynamics: A Brief Introduction / Alessandro Moura, Celso Grebogi -- Qualitative Inference in Dynamical Systems / Fatihcan M Atay, Jurgen Jost -- Stochastic Dynamical Systems / Darren J Wilkinson -- Gaussian Process Inference for Differential Equation Models of Transcriptional Regulation / Neil Lawrence, Magnus Rattray, Antti Honkela, Michalis Titsias -- Model Identification by Utilizing Likelihood-Based Methods / Andreas Raue, Jens Timmer -- Application Areas. Inference of Signalling Pathway Models / Tina Toni, Juliane Liepe, Michael P H Stumpf -- Modelling Transcription Factor Activity / Martino Barenco, Daniel Brewer, Robin Callard, Michael Hubank -- Host-Pathogen Systems Biology / John W Pinney -- Bayesian Approaches for Mass Spectrometry-Based Metabolomics / Simon Rogers, Richard A Scheltema, Michael Barrett, Rainer Breitling -- Systems Biology of microRNAs / Doron Betel, Raya Khanin.
520 _aSystems Biology is now entering a mature phase in which the key issues are characterising uncertainty and stochastic effects in mathematical models of biological systems. The area is moving towards a full statistical analysis and probabilistic reasoning over the inferences that can be made from mathematical models. This handbook presents a comprehensive guide to the discipline for practitioners and educators, in providing a full and detailed treatment of these important and emerging subjects. Leading experts in systems biology and statistics have come together to provide insight in to the major ideas in the field, and in particular methods of specifying and fitting models, and estimating the unknown parameters.
588 0 _aPrint version record.
650 0 _aSystems biology
_xStatistical methods
_vHandbooks, manuals, etc.
650 0 _aBiological systems
_xMathematical models
_vHandbooks, manuals, etc.
650 0 _aStochastic analysis
_xMathematical models
_vHandbooks, manuals, etc.
650 4 _aElectronic resource.
655 4 _aElectronic resource.
700 1 _aStumpf, M. P. H.
_q(Michael P. H.)
700 1 _aBalding, D. J.
700 1 _aGirolami, Mark,
_d1963-
710 2 _aWiley InterScience (Online service)
773 0 _tWiley e-books
856 4 0 _uhttps://eresourcesptsl.ukm.remotexs.co/user/login?url=https://doi.org/10.1002/9781119970606
_zWiley Online Library
907 _a.b16667323
_b2022-10-12
_c2019-11-12
942 _n0
914 _avtls003642052
998 _ae
_b2018-06-12
_cm
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_feng
_genk
_y0
_z.b16667323
999 _c634868
_d634868