000			04135nam a2200469 a 4500
005			20250918191358.0
008			130603s2011 enka b 001 0 eng
020			_a9780521194280 _cRM405.00
020			_a0521194288
039		9	_a201504061232 _bsue _c201504031756 _dsue _c201501121538 _dwafi _c201311080950 _dhayat _y06-03-2013 _zros
040			_dUKM _erda
090			_aQH506.M63
090			_aQH506 _b.M63
090			_aQH506 _b.M718c 2011 9HUKMPRA
245	0	0	_aMolecular machines in biology : _bworkshop of the cell / _cedited by Joachim Frank.
264		4	_c©2011
264		1	_aCambridge : _bCambridge University Press, _c[2011].
300			_axiii, 272 pages : _billustrations (chiefly col.) ; _c29 cm.
504			_aIncludes bibliographical references and index.
505	0	0	_g1. _tSingle-molecule FRET: technique and applications to the studies of molecular machines / _rXinghua Shi and Taekjip Ha -- _g2. _tVisualization of molecular machines by cryo-electron microscopy / _rJoachim Frank -- _g3. _tStatistical mechanical treatment of molecular machines / _rDebashish Chowdhury -- _g4. _tExploring the functional landscape of biomolecular machines via elastic network normal mode analysis / _rKarunesh Arora and Charles L. Brooks III -- _g5. _tStructure, function, and evolution of archaeo-eukaryotic RNA polymerases -- gatekeepers of the genome / _rFinn Werner and Dina Grohmann -- _g6. _tSingle-molecule fluorescence resonance energy transfer investigations of ribosome-catalyzed protein synthesis / _rDaniel D. MacDougall, Jingyi Fei and Ruben L. Gonzalez, Jr. -- _g7. _tStructure and dynamics of the ribosome as revealed by cryo-electron microscopy / _rXabier Agirrezabala and Mikel Valle -- _g8. _tViewing the mechanisms of translation through the computational microscope / _rJames Gumbart, Eduard Schreiner, Leonardo G. Trabuco, Kwok-Yan Chan and Klaus Schulten -- _g9. _tThe ribosome as a Brownian ratchet machine / _rAlexander S. Spirin and Alexei V. Finkelstein -- _g10. T _the GroEL/GroES chaperonin machine / _rArthur L. Horwich and Helen R. Saibil -- _g11. _tATP synthase -- a paradigmatic molecular machine / _rThomas Meier, Jose; Faraldo-Gez and Michael B诲sch -- _g12. _tATP-dependent proteases: the cell's degradation machines / _rSucharita Bhattacharyya, Shameika R. Wilmington and Andreas Matouschek.
520			_a'This edited volume discusses the concept of molecular machines, their intricate architecture, and new techniques that are being used to better understand the processes in the cell driven by molecular machines'--Provided by publisher.
520			_a'The concept of molecular machines in biology has transformed the medical field in a profound way. Many essential processes that occur in the cell, including transcription, translation, protein folding, and protein degradation, are all carried out by molecular machines. This volume focuses on important molecular machines whose architecture is known and whose functional principles have been established by tools of biophysical imaging (X-ray crystallography and cryo-electron microscopy) and fluorescence probing (single-molecule FRET). This edited volume includes contributions from prominent scientists and researchers who understand and have explored the structure and functions of these machines. This book is essential for students and professionals in the medical field who want to learn more about molecular machines'--Provided by publisher.
650		0	_aMicrobiology.
650		0	_aMolecular biology.
650		0	_aBiochemistry.
650		0	_aCell physiology.
650		0	_aElectron microscopy.
650	1	2	_aMolecular Biology.
650	2	2	_aCell Physiological Phenomena.
650	2	2	_aComputational Biology.
650	2	2	_aMicrobiology.
650	2	2	_aModels, Biological.
700	1		_aFrank, J. _q(Joachim), _d1940-
907			_a.b15648692 _b2019-11-12 _c2019-11-12
942			_c01 _n0 _kQH506.M63
914			_avtls003531357
990			_abaiti/sue
991			_aFakulti Kejuruteraan dan Alam Bina
991			_aJabatan Biologi, Pra Klinikal PPUKM
998			_ap _at _b2013-03-06 _cm _da _feng _genk _y0 _z.b15648692
999			_c547604 _d547604