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| 008 | 110419s2010 enka b 001 0 eng | ||
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_a9781849730167 (hbk.) _cRM680.44 |
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_a201107281509 _bzainol _c201106100923 _drazalis _y04-19-2011 _zrazalis |
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_aQV38 _b.M588 2010 9 |
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| 090 | _aQV38.M588 2010 9 | ||
| 245 | 0 | 0 |
_aMetabolism, pharmacokinetics, and toxicity of functional groups : _bimpact of the building blocks of medicinal chemistry in ADMET / _cedited by Dennis A. Smith |
| 260 |
_aCambridge, [England] : _bRoyal Society of Chemistry, _c2010 |
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| 300 |
_axiv, 530 p. : _bill. ; _c25 cm. |
||
| 490 | 1 |
_aRSC drug discovery series, _x2041-3203 ; _vno. 1 |
|
| 505 | 0 | _aDrugs and their structural motifs -- ADMET for the medicinal chemist -- Carboxylic acids and their bioisosteres -- Primary, secondary, and tertiary amines and their isosteres -- Sulfonamide as an essential functional group in drug design -- Influence of aromatic rings on ADME properties of drugs -- Influence of heteroaromatic rings on ADME properties -- Peptidomimetics and peptides as drugs: motifs incorporated to enhance drug characteristics -- Pharmacokinetics and metabolism of compounds that mimic enzyme transition states -- Alcohols and phenols: absorption, distribution, metabolism, and excretion -- Future targets and chemistry and ADME needs | |
| 650 | 2 | _aPharmacokinetics | |
| 650 | 2 |
_aChemistry, Pharmaceutical _xmethods |
|
| 650 | 2 |
_aPharmaceutical Preparations _xmetabolism |
|
| 700 | 1 | _aSmith, Dennis A. | |
| 710 | 2 | _aRoyal Society of Chemistry (Great Britain) | |
| 907 |
_a.b15005525 _b2019-11-12 _c2019-11-12 |
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| 991 | _aJabatan Farmasi, KKL | ||
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