000 01893pam a2200325 a 4500
005 20250918140433.0
008 110419s2010 enka b 001 0 eng
020 _a9781849730167 (hbk.)
_cRM680.44
020 _a1849730164 (hbk.)
039 9 _a201107281509
_bzainol
_c201106100923
_drazalis
_y04-19-2011
_zrazalis
040 _aUKM
060 _aQV38
_b.M588 2010 9
090 _aQV38.M588 2010 9
245 0 0 _aMetabolism, pharmacokinetics, and toxicity of functional groups :
_bimpact of the building blocks of medicinal chemistry in ADMET /
_cedited by Dennis A. Smith
260 _aCambridge, [England] :
_bRoyal Society of Chemistry,
_c2010
300 _axiv, 530 p. :
_bill. ;
_c25 cm.
490 1 _aRSC drug discovery series,
_x2041-3203 ;
_vno. 1
505 0 _aDrugs and their structural motifs -- ADMET for the medicinal chemist -- Carboxylic acids and their bioisosteres -- Primary, secondary, and tertiary amines and their isosteres -- Sulfonamide as an essential functional group in drug design -- Influence of aromatic rings on ADME properties of drugs -- Influence of heteroaromatic rings on ADME properties -- Peptidomimetics and peptides as drugs: motifs incorporated to enhance drug characteristics -- Pharmacokinetics and metabolism of compounds that mimic enzyme transition states -- Alcohols and phenols: absorption, distribution, metabolism, and excretion -- Future targets and chemistry and ADME needs
650 2 _aPharmacokinetics
650 2 _aChemistry, Pharmaceutical
_xmethods
650 2 _aPharmaceutical Preparations
_xmetabolism
700 1 _aSmith, Dennis A.
710 2 _aRoyal Society of Chemistry (Great Britain)
907 _a.b15005525
_b2019-11-12
_c2019-11-12
942 _c01
_n0
_kQV38.M588 2010 9
914 _avtls003462751
991 _aJabatan Farmasi, KKL
998 _ad
_b2011-06-04
_cm
_da
_feng
_genk
_y0
_z.b15005525
999 _c485315
_d485315