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090 _aQV350.W223a 2003
100 1 _aWalsh, Christopher
245 1 0 _aAntibiotics :
_bactions, origins, resistance /
_cby Christopher Walsh
260 _aWashington :
_bASM Press,
_c2003
300 _ax, 335 p. :
_bill. ;
_c26 cm.
504 _aReferences : p. 297-328
505 0 _aAntibiotics: initial concepts -- Introduction to major antibiotic classes and modes of action -- Antibiotics that act on cell wall biosynthesis -- Antibiotics that block bacterial protein biosynthesis -- Antibiotics that block DNA replication and repair: the quinolones -- Other targets of antibacterial drugs -- Natural and producer immunity versus acquired resistance -- Enzymatic destruction or modification of the antibiotic by resistant bacteria -- Antibiotic resistance by efflux pumps -- Antibiotic resistance by replacement or modification of the antibiotic target -- Regulation of antibiotic biosynthesis in producer organisms -- Polyketide antibiotic biosynthesis: assembly-line enzymology -- Enzymatic assembly lines for nonribosomal peptide antibiotics -- Biosynthesis of other classes of antibiotics -- New looks at targets -- New molecules -- Contexts and challenges for the use of new antibiotics
650 2 _aAntibiotics
_xpharmacology
650 2 _aDrug Resistance, Bacterial
907 _a.b13258576
_b2019-11-12
_c2019-11-12
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_kQV350.W223a 2003
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990 _adh
991 _aJabatan Makmal Diagnostik, HUKM
991 _aJabatan Farmasi
998 _ad
_ah
_b2003-11-09
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