Understanding and exploiting protein-protein interactions as drug targets / editor, Giovanna Zinzalla.

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Includes bibliographical references and index.

Understanding and exploiting protein-protein interactions as drug targets / Giovanna Zinzalla -- Protein-protein interactions : an emerging class of molecular targets for anticancer drugs / Alex W. White, Jitka Soukupov& Andrew D. Westwell -- Druggability of protein-protein interactions / Veronique Hamon & Xavier Morelli -- Chemical library screening approaches to aid the design of protein-protein inhibitors / Luca Laraia & David R. Spring -- Peptides as protein-protein interaction modulators / Erika Nieddu, Luisa Merello & Carlo Bidoia -- Constrained peptide helices / Andrew B. Mahon & Paramjit S. Arora -- Synthesis of peptidomimetic scaffolds / Andrew J. Wilson -- Computational approaches for the design of protein-protein interaction inhibitors / Wenbo Yu, Olgun Guvench & Alexander D. MacKerell Jr. -- Biochemical assays and biophysical tools for inhibitor identification and validation / Adrian Fowkes, Helene Bertrand & Geoff Wells -- Cell-based assays for identifying, validating and optimizing protein-protein interaction modulators / Abigail L. Male & Ali Tavassoli -- Future directions / Alexander L. Breeze -- Index.

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