Drug delivery and development of anti-HIV microbicides / edited by, Jose das Neves, Bruno Sarmento.

Includes bibliographical references and index.

1. Microbicides for the prevention of HIV / Osmond J. D'Cruz and Fatih M. Uckun -- 2. HIV transmission models : lessons learned for microbicide formulation design / Pedro M.M. Mesquita and Betsy C. Herold -- 3. Challenges in microbicide drug delivery : identifying targets and evolving strategies / Karolin Hijazi, Constandinos Carserides, and Charles Kelly -- 4. Safety aspects of topical anti-HIV microbicides / Raina N. Fichorova -- 5. Biophysics, drug transport modeling, and performance of microbicides / David F. Katz -- 6. Dosage forms for microbicide formulations : advantages and pitfalls / Viness Pillay, Pradeep Kumar, Valence M.K. Ndesendo, Yahya E. Choonara, and Lisa du Toit -- 7. Microbicide intravaginal rings / John A. Moss and Marc M. Baum -- 8. Vaginal microbicide films / Lisa C. Rohan and Wei Zhang -- 9. The development of rectal microbicides for HIV-1 prevention / Ian McGowan, Charlene S. Dezzutti, and Lisa C. Rohan -- 10. Design of stimuli-sensitive microbicide formulations / Chi H. Lee and Namita Giri -- 11. Nanotechnology-based systems for microbicide development / Rute Nunes, Carole Sousa, Bruno Sarmento, and Josdas Neves -- 12. Electrospun fibers for microbicide drug delivery / Cameron Ball and Kim A. Woodrow -- 13. Modified microbiota for microbicide drug delivery / Luca Vangelista and Massimiliano Secchi -- 14. Microbicide formulation development : scale-up, affordability, and intellectual property issues / David R. Friend, Br{u2A64} Devlin, and Christopher Gilmour -- 15. Regulatory issues pertaining to microbicide development / Linda Arterburn, Lisa Carlton, and Zeda Rosenberg -- 16. Socioeconomic and behavioral factors influencing choice, adherence, and success of microbicide formulations / Elizabeth Tolley, Barbara Friedland, Mitzy Gafos, Rivet Amico, Lut van Damme, Cynthia Woodsong, Kathleen MacQueen, Leila Mansoor, and Sheena McCormack.