Small GTPases in disease, Part A / edited by William E. Balch, Channing J. Der, and Alan Hall

Includes bibliographical references and indexes

1. Rab1b Silencing Using Small Interfering RNA for Analysis of Disease-Specific Function / Darren M. Hutt, William E. Balch -- 2. Rab8-Optineurin-Myosin VI: Analysis of Interactions and Functions in the Secretory Pathway / Margarita V. Chibalina ... [et al.] -- 3. Characterization of Rab27a and JFC1 as Constituents of the Secretory Machinery of Prostate-Specific Antigen in Prostate Carcinoma Cells / Sergio D. Catz -- 4. In Vitro Assays to Characterize Inhibitors of the Activation of Small G Proteins by Their Guanine Nucleotide Exchange Factors / Jean-Christophe Zeeh ... [et al.] -- 5. Analysis of Small GTPase Function in Trypanosomes / Mark C. Field, David Horn, Mark Carrington -- 6. Use of Dynasore, the Small Molecule Inhibitor of Dynamin, in the Regulation of Endocytosis / Tom Kirchhausen, Eric Macia, Henry E. Pelish -- 7. Identification and Verification of Sro7p as an Effector of the Sec4p Rab GTPase / Bianka L. Grosshans, Peter Novick -- 8. Characterization of Rab18, a Lipid Droplet-Associated Small GTPase / Sally Martin, Robert G. Parton -- 9. Analysis on the Emerging Role of Rab3 GTPase-Activating Protein in Warburg Micro and Martsolf Syndrome / Ayuko Sakane ... [et al.]i --

10. Identification and Characterization of JRAB/MICAL-L2, a Junctional Rab13-Binding Protein / Noriyuki Nishimura, Takuya Sasaki -- 11. A SMAP Gene Family Encoding ARF GTPase-Activating Proteins and Its Implication in Membrane Trafficking / Kenji Tanabe ... [et al.] -- 12. In Vitro and In Vivo Analysis of Neurotrophin-3 Activation of Arf6 and Rac-1 / Pedro F. Esteban ... [et al.] -- 13. Methods for Analysis of rab27a/munc13-4 in Secretory Lysosome Release in Hematopoietic Cells / Peter van der Sluijs ... [et al.] -- 14. Analysis and Expression of Rab38 in Oculocutaneous Lung Disease / Kazuhiro Osanai, Dennis R. Voelker -- 15. Analysis of Rab1 Function in Cardiomyocyte Growth / Catalin M. Filipeanu, Fuguo Zhou, Guangyu Wu -- 16. Regulation of the Trafficking and Function of G Protein-Coupled Receptors by Rab1 GTPase in Cardiomyocytes / Guangyu Wu -- 17. Regulation of Endosome Dynamics by Rab5 and Huntingtin-HAP40 Effector Complex in Physiological versus Pathological Conditions / Arun Pal ... [et al]. --

19. Biochemical Characterization of Novel Germline BRAF and MEK Mutations in Cardio-Facio-Cutaneous Syndrome / Pablo Rodriguez-Viciana, Katherine A. Rauen -- 20. Biochemical and Biological Characterization of Tumor-Associated Mutations of p110 [alpha] / Adam Denley ... [et al.] -- 21. Characterization of the Rheb-mTOR Signaling Pathway in Mammalian Cells: Constitutive Active Mutants of Rheb and mTOR / Tatsuhiro Sato, Akiko Umetsu, Fuyuhiko Tamanoi -- 22. Characterization of RalB-Sec5-TBK1 Function in Human Oncogenesis / Yuchen Chien, Michael A. White -- 23. High-Throughput Lung Cancer Cell Line Screening for Genotype-Correlated Sensitivity to an EGFR Kinase Inhibitor / Ultan McDermott, Sreenath V. Sharma, Jeffrey Settleman -- 24. In Vitro Signaling by MAPK and NF[kappa]B Pathways Inhibited by Yersinia YopJ / Sohini Mukherjee, Kim Orth -- 25. Biological and Biochemical Characterization of Anthrax Lethal Factor, a Proteolytic Inhibitor of MEK Signaling Pathways / Jennifer L. Bromberg-White, Nicholas S. Duesbery -- 26. Genetic Analyses of the Role of RCE1 in RAS Membrane Association and Transformation / Martin O. Bergo ... [et al.] -- 27. Characterization of Kras-Mediated Pancreatic Tumorigenesis in Zebrafish / Jon M. Davison ... [et al.] -- 28. Genetic Modeling of Ras-Induced Human Rhabdomyosarcoma / Corinne M. Linardic, Christopher M. Counter