Systems metabolic engineering : methods and protocols / edited by Hal S. Alper.

Includes bibliographical references and index.

Genome-scale model management and comparison / Stephan Pabinger and Zlatko Trajanoski -- Automated genome annotation and metabolic model reconstruction in the SEED and model SEED / Scott Devoid ... [et al.] -- Metabolic model refinement using phenotypic microarray data / Pratish Gawand ... [et al.] -- Linking genome-scale metabolic modeling and genome annotation / Edik M. Blais, Arvind K. Chavali, and Jason A. Papin -- Resolving cell composition through simple measurements, genome-scale modeling, and a genetic algorithm / Ryan S. Senger and Hadi Nazem-Bokaee -- Guide to integrating transcriptional regulatory and metabolic networks using PROM (probabilistic regulation of metabolism) / Evangelos Simeonidis, Sriram Chandrasekaran, and Nathan D. Price -- Kinetic modeling of metabolic pathways : application to serine biosynthesis / Kieran Smallbone and Natalie J. Stanford -- Computational tools for guided discovery and engineering of metabolic pathways / Matthew Moura, Linda Broadbelt, and Keith Tyo -- Retrosynthetic design of heterologous pathways / Pablo Carbonell, Anne-Gaelle Planson, and Jean-Loup Faulon -- Customized optimization of metabolic pathways by combinatorial transcriptional engineering / Yongbo Yuan, Jing Du, and Huimin Zhao -- Adaptive laboratory evolution for strain engineering / James Winkler, Luis H. Reyes, and Katy C. Kao -- Trackable multiplex recombineering for gene-trait mapping in E. coli / Thomas J. Mansell, Joseph R. Warner, and Ryan T. Gill -- Identification of mutations in evolved bacterial genomes / Liam Royce ... [et al.] -- Discovery of posttranscriptional regulatory RNAs using next generation sequencing technologies / Grant Gelderman and Lydia M. Contreras -- 13C-based metabolic flux analysis : fundamentals and practice / Tae Hoon Yang -- Nuclear magnetic resonance methods for metabolic fluxomics / Shilpa Nargund ... [et al.] -- Using multiple tracers for 13C metabolic flux analysis / Maciek R. Antoniewicz -- Isotopically nonstationary 13C metabolic flux analysis / Lara J. Jazmin and Jamey D. Young -- Sample preparation and biostatistics for integrated genomics approaches / Hein Stam ... [et al.] -- Targeted metabolic engineering guided by computational analysis of single-nucleotide polymorphisms (SNPs) / D.B.R.K. Gupta Udatha ... [et al.] -- Linking RNA measurements and proteomics with genome-scale models / Christopher M. Gowen and Stephen S. Fong -- Comparative transcriptome analysis for metabolic engineering / Shuobo Shi, Tao Chen, and Xueming Zhao -- Merging multiple omics datasets in silico : statistical analyses and data interpretation / Kazuharu Arakawa and Masaru Tomita.