Kinomics : approaches and applications /
edited by Heinz-Bernhard Kraatz and Sanela Martic.
- 1 online resource.
Includes bibliographical references and index.
Part I: Protein Kinases Cell Signaling. Global Approaches to Understanding Protein Kinase Functions / Jennifer L Gorman, James R Woodgett --'Genuine' Casein Kinase (Fam20C): The Mother of the Phosphosecretome / Giorgio Cozza, Vincent S Tagliabracci, Jack E Dixon, Lorenzo A Pinna -- Chemical Biology of Protein Kinases / David Mann -- Protein Kinases and Caspases: Bidirectional Interactions in Apoptosis / Stephanie A Zukowski, David W Litchfield -- The Kinomics of Malaria / Mathieu Brochet, Andrew B Tobin, Oliver Billker, Christian Doerig -- Part II: ATP Co-substrate Design. ATP Analogs in Protein Kinase Research / Thilani M Anthony, Pavithra M Dedigama-Arachchige, D Maheeka Embogama, Todd R Faner, Ahmed E Fouda, Mary Kay H Pflum -- Electrochemical Detection of Protein Kinase-Catalyzed Phosphorylations / Sanela Martic, Soha Ahmadi, Zhe She, Heinz-Bernhard Kraatz -- Part III: New Methodologies for Kinomics. Phos-tag Technology for Kinomics / Emiko Kinoshita-Kikuta, Eiji Kinoshita, Tohru Koike -- Development of Species- and Process-Specific Peptide Kinome Arrays with Priority Application to Investigations of Infectious Disease / Ryan Arsenault, Brett Trost, Anthony Kusalik, Scott Napper -- New Approaches to Understanding Bacterial Histidine Kinase Activity and Inhibition / Kaelyn E Wilke, Erin E Carlson -- Methods for Large-Scale Identification of Protein Kinase Substrate Networks / KassaDee J Ketelaar, Ian S Wallace -- Part IV: Kinase Inhibition. Developing Inhibitors of STAT3: Targeting Downstream of the Kinases for Treating Disease / Andrew M Lewis, Daniel P Ball, Rahul Rana, Ji Sung Park, David Rosa, Ping-Shan Lai, Rodolfo F Gómez-Biagi, Patrick T Gunning -- Metal Compounds as Kinase and Phosphatase Inhibitors in Drug Development: The Role of the Metal and Ligands / Maria V Babak, Margaux Airey, Christian G Hartinger.