Antimicrobial peptides /
David A. Phoenix, Sarah R. Dennison, and Frederick Harris.
- 1 online resource (xv, 231 pages) : illustrations (some color)
Includes bibliographical references and index.
Antimicrobial peptides: their history, evolution, and functional promiscuity -- Cationic antimicrobial peptides -- Anionic antimicrobial peptides -- Graphical techniques to visualize the amphiphilic structures of antimicrobial peptides -- Models for the membrane interactions of antimicrobial peptides -- Selectivity and toxicity of oncolytic antimicrobial peptides.
In this didactically-written text, the small team of expert authors presents the field in a comprehensive and accessible manner that is well suited for students and junior researchers. The result is a highly readable and systematically structured introduction to antimicrobial peptides, their structure, biological function and mode of action. The authors point the way towards a rational design of this potentially highly effective new class of clinical antibiotics on the brink of industrial application by discussing their design principles, target membranes and structure-activity relationship.