TY - BOOK AU - Peppin,John F. AU - Pergolizzi,Joseph V. AU - Raffa,Robert B. AU - Wright,Steven L. TI - The benzodiazepines crisis: the ramifications of an over-used drug class T2 - Oxford medicine online SN - 9780197517307 (ebook) : AV - RM666.B42 U1 - 615.7882 23 PY - 2020/// CY - New York, NY PB - Oxford University Press KW - Benzodiazepines KW - Pharmacokinetics KW - Benzodiazepine abuse KW - Drug withdrawal symptoms N1 - Also issued in print: 2020; Includes bibliographical references and index; Specialized N2 - Misused, abused, diverted, and counterfeited, benzodiazepines have serious potential for substance use disorder, and are among the leading causes of drug-related overdose deaths. Evidence indicates that prolonged use of benzodiazepines causes a wide range of adverse reactions, and withdrawal can be particularly challenging. Nevertheless, these negative aspects have yet to be thoroughly addressed within the medical community and remain virtually unknown to patients. This text offers an in-depth discussion of the downsides of this overused class of drugs and calls for their rational and dramatically reduced usage UR - http://dx.doi.org/10.1093/med/9780197517277.001.0001 ER -