Reversible ligand binding : theory and experiment /
by Andrea Bellelli, Jannette Carey.
- First edition.
- 1 online resource.
Includes bibliographical references and index.
Ligand Binding to Single Binding Site Targets. Theory of Ligand Binding to Monomeric Proteins -- Ligand-Binding Kinetics for Single-Site Proteins -- Practical Considerations and Commonly Encountered Problems -- Ligand Binding to Multiple Binding Site Proteins. Proteins with Multiple Binding Sites -- Ligand-Linked Association and Dissociation -- Kinetics of Ligand Binding to Proteins with Multiple Binding Sites -- Hemoglobin and its Ligands -- Enzymes. Single-Substrate Enzymes and their Inhibitors -- Two-Substrate Enzymes and their Inhibitors -- Beyond the Steady State -- Slowly Binding and Irreversible Enzyme Inhibitors.