TY  - BOOK
AU  - Ecker,Gerhard F.
AU  - Clausen,Rasmus P.
AU  - Sitte,Harald
TI  - Transporters as Drug Targets
T2  - Methods and principles in medicinal chemistry
SN  - 9783527679430
AV  - QP552.C34 
U1  - 572/.696 23
PY  - 0000///ò017
CY  - Weinheim, Germany
PB  - Wiley-VCH
KW  - Carrier proteins
KW  - Drug targeting
KW  - SCIENCE / Life Sciences / Biochemistry
KW  - bisacsh
KW  - fast
KW  - Drug carriers
KW  - Electronic books
N2  - As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets. Following a general introduction to the importance of targeting transporter proteins with drugs, the book systematically presents individual transporter classes and explains their pharmacology and physiology. The text covers all transporter families with known or suspected importance as drug targets, including neurotransmitter transporters, ABC transporters, glucose transporters and organic ion transporters. The final part discusses recent advances in structural studies of transport proteins, assay methods for transport activity, and the systems biology of transporters and their regulation. With its focus on drug development issues, this authoritative overview is required reading for researchers in industry and academia targeting transport proteins for the treatment of disease
UR  - http://www.ezplib.ukm.edu.my/login?url=https://doi.org/10.1002/9783527679430
ER  -