Transporters as Drug Targets. - 1 online resource. - Methods and principles in medicinal chemistry ; v. 70 . - Methods and principles in medicinal chemistry ; v. 70. .

As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets. Following a general introduction to the importance of targeting transporter proteins with drugs, the book systematically presents individual transporter classes and explains their pharmacology and physiology. The text covers all transporter families with known or suspected importance as drug targets, including neurotransmitter transporters, ABC transporters, glucose transporters and organic ion transporters. The final part discusses recent advances in structural studies of transport proteins, assay methods for transport activity, and the systems biology of transporters and their regulation. With its focus on drug development issues, this authoritative overview is required reading for researchers in industry and academia targeting transport proteins for the treatment of disease.

9783527679430 352767943X 3527679510 9783527679522 3527679529 9783527679515

979303 MIL


Carrier proteins.
Drug targeting.
SCIENCE / Life Sciences / Biochemistry
Carrier proteins.
Drug targeting.
Drug carriers.


Electronic books.

QP552.C34

572/.696

QV 785