TY - BOOK AU - Zinzalla,Giovanna ED - Future Science Ltd., TI - Understanding and exploiting protein-protein interactions as drug targets T2 - The Future Science Group eBook collection, PY - 2013///] CY - London, England PB - Future Science Ltd KW - Drug Discovery KW - methods KW - Proteins KW - Metabolism KW - Electronic books N1 - Page 152 is blank; Includes bibliographical references and index; Understanding and exploiting protein-protein interactions as drug targets / Giovanna Zinzalla -- Protein-protein interactions : an emerging class of molecular targets for anticancer drugs / Alex W. White, Jitka Soukupov& Andrew D. Westwell -- Druggability of protein-protein interactions / Veronique Hamon & Xavier Morelli -- Chemical library screening approaches to aid the design of protein-protein inhibitors / Luca Laraia & David R. Spring -- Peptides as protein-protein interaction modulators / Erika Nieddu, Luisa Merello & Carlo Bidoia -- Constrained peptide helices / Andrew B. Mahon & Paramjit S. Arora -- Synthesis of peptidomimetic scaffolds / Andrew J. Wilson -- Computational approaches for the design of protein-protein interaction inhibitors / Wenbo Yu, Olgun Guvench & Alexander D. MacKerell Jr. -- Biochemical assays and biophysical tools for inhibitor identification and validation / Adrian Fowkes, Helene Bertrand & Geoff Wells -- Cell-based assays for identifying, validating and optimizing protein-protein interaction modulators / Abigail L. Male & Ali Tavassoli -- Future directions / Alexander L. Breeze -- Index; Restricted to subscribers or individual electronic text purchasers; Also available in print UR - https://doi-org.eresourcesptsl.ukm.remotexs.co/10.4155/9781909453463 UR - https://doi.org/10.4155/9781909453463 ER -