TY  - BOOK
AU  - Zheng,Y.George
TI  - Epigenetic technological applications
T2  - Translational epigenetics series
SN  - 9780128013274
AV  - QH450 
U1  - 572.865 23
PY  - 2015///]
CY  - Amsterdam
PB  - Academic Press
KW  - Epigenetics
KW  - Genetic Therapy
KW  - Acetylation
KW  - DNA Methylation
KW  - genetics
KW  - Epigenomics
KW  - Genetic Predisposition to Disease
KW  - SCIENCE / Life Sciences / Biochemistry
KW  - bisacsh
KW  - fast
KW  - Electronic books
N1  - Includes bibliographical references and index; The state of the art of epigenetic technologies -- Technologies for the measurement and mapping of genomic 5-methylcytosine and 5-hydroxymethylcytosine -- High-throughput sequencing-based mapping of cytosine modifications -- Application of mass spectrometry in translational epigenetics -- Techniques analyzing chromatin modifications at specific single loci -- Comprehensive analysis of mammalian linker-histone variants and their mutants -- Crystallography-based mechanistic insights into epigenetic regulation -- Chemical and genetic approaches to study histone modifications -- Peptide microarrays for profiling of epigenetic targets -- Current methods for methylome profiling -- Bioinformatics and biostatistics in mining epigenetic disease markers and targets -- Computational modeling to elucidate molecular mechanisms of epigenetic memory -- DNA methyltransferase inhibitors for cancer therapy -- Histone acetyltransferases: enzymes, assays, and inhibitors -- In vitro histone deacetylase activity screening: making a case for better assays -- Enzymatic assays of histone methyltransferase enzymes -- Histone methyltransferase inhibitors for cancer therapy -- Discovery of histone demethylase inhibitors -- Histone demethylases: background, purification, and detection -- Animal model study of epigenetic inhibitors -- Index
UR  - https://eresourcesptsl.ukm.remotexs.co/user/login?url=http://www.sciencedirect.com/science/book/9780128010808
ER  -