TY - BOOK AU - Caruso,Gerardo AU - Mero,Lucia AU - Caffo,Maria TI - Innovative brain tumor therapy: nanoparticle-based therapeutic strategies T2 - Woodhead Publishing series in biomedicine SN - 9781908818744 AV - RD663 .C37 2014 U1 - 616.99/48106 23 PY - 0000///ò014 CY - Amersterdam PB - Elsevier Science KW - Brain KW - Tumors KW - Nanoparticles KW - therapeutic use KW - HEALTH & FITNESS KW - Diseases KW - General KW - bisacsh KW - MEDICAL KW - Clinical Medicine KW - Evidence-Based Medicine KW - Internal Medicine KW - Electronic books N1 - Includes bibliographical references and index N2 - Despite recent advances, therapeutic efforts have not been successful establishing a definitive strategy of treatment for brain gliomas, because of the presence of the blood-brain barrier. Innovative Brain Tumor Therapy presents a synopsis of the studies on nanoparticles as ideal devices for brain tumor treatment. Their nanometric size, electrostatic charge, and lipophilic characteristics allow them to penetrate into the brain tissue freely. Promising in-vitro results have been reported, but remain to be validated in humans. This title focuses on the blood-brain barrier pathophysiology in brain tumors, and the possibilities of overcoming this with nanoparticle-based systems. Relevant patents of nanoparticles used as drug delivery carriers are also reported, as well as future scenarios in nanoparticles and stem cells UR - http://ezplib.ukm.my/login?url=http://www.sciencedirect.com/science/book/9781907568596 ER -