Drug delivery and development of anti-HIV microbicides / edited by, Jose das Neves, Bruno Sarmento. - xxii, 684 pages : illustrations ; 24 cm.

Includes bibliographical references and index.

1. Microbicides for the prevention of HIV / Osmond J. D'Cruz and Fatih M. Uckun -- 2. HIV transmission models : lessons learned for microbicide formulation design / Pedro M.M. Mesquita and Betsy C. Herold -- 3. Challenges in microbicide drug delivery : identifying targets and evolving strategies / Karolin Hijazi, Constandinos Carserides, and Charles Kelly -- 4. Safety aspects of topical anti-HIV microbicides / Raina N. Fichorova -- 5. Biophysics, drug transport modeling, and performance of microbicides / David F. Katz -- 6. Dosage forms for microbicide formulations : advantages and pitfalls / Viness Pillay, Pradeep Kumar, Valence M.K. Ndesendo, Yahya E. Choonara, and Lisa du Toit -- 7. Microbicide intravaginal rings / John A. Moss and Marc M. Baum -- 8. Vaginal microbicide films / Lisa C. Rohan and Wei Zhang -- 9. The development of rectal microbicides for HIV-1 prevention / Ian McGowan, Charlene S. Dezzutti, and Lisa C. Rohan -- 10. Design of stimuli-sensitive microbicide formulations / Chi H. Lee and Namita Giri -- 11. Nanotechnology-based systems for microbicide development / Rute Nunes, Carole Sousa, Bruno Sarmento, and Josdas Neves -- 12. Electrospun fibers for microbicide drug delivery / Cameron Ball and Kim A. Woodrow -- 13. Modified microbiota for microbicide drug delivery / Luca Vangelista and Massimiliano Secchi -- 14. Microbicide formulation development : scale-up, affordability, and intellectual property issues / David R. Friend, Br Devlin, and Christopher Gilmour -- 15. Regulatory issues pertaining to microbicide development / Linda Arterburn, Lisa Carlton, and Zeda Rosenberg -- 16. Socioeconomic and behavioral factors influencing choice, adherence, and success of microbicide formulations / Elizabeth Tolley, Barbara Friedland, Mitzy Gafos, Rivet Amico, Lut van Damme, Cynthia Woodsong, Kathleen MacQueen, Leila Mansoor, and Sheena McCormack.

9789814463560 (hardcover) RM 897.24 9814463566 (hardcover) 9789814463577 (eBook) 9814463574 (eBook)


HIV Infections--prevention & control.
Anti-infective agents.
Drug delivery systems.
HIV Infections--drug therapy.