Basic pharmacokinetics and pharmacodynamics : an integrated textbook and computer simulations - Rosenbaum, Sara (Sara E.) (Hoboken, N.J. : John Wiley & Sons, 2011)
Introduction to pharmacokinetics and pharmacodynamics -- Passage of drug through membranes -- Drug absorption -- Drug elimination -- Compartmental models -- Pharmacokinetics of an intravenous bolus injection in a one compartment model -- An intravenous bolus injection in the two compartment model -- Pharmacokinetics of extravascular drug administration -- Introduction to non-compartmental analysis -- Pharmacokinetics of the intravenous infusion in a one compartment model -- Multiple intravenous bolus injections in the one compartment model -- Multiple intermittent infusions -- Multiple oral doses -- Nonlinear pharmacokinetics -- Introduction to pharmacodynamic models and integrated pharmacokinetic- pharmacodynamics (PK-PD) models -- Mechanism based integrated pharmacokinetic-pharmacodynamic models.
Includes bibliographical references and index.
Keywords: Pharmacokinetics; Computer simulation; Pharmacological Phenomena