TY  - BOOK
AU  - Cannataro,Mario
AU  - Guzzi,Pietro Hiram
TI  - Data management of protein interaction networks
T2  - Wiley series in bioinformatics
SN  - 9780470770405 (hbk.)
PY  - 2011///
CY  - Hoboken, New Jersey
PB  - John Wiley & Sons
KW  - Protein-protein interaction
KW  - Information resources
KW  - Information resources management
N2  - 'Current PPI databases do not offer sophisticated querying interfaces and especially do not integrate existing information about proteins. Current algorithms for PIN analysis use only topological information, while emerging approaches attempt to exploit the biological knowledge related to proteins and kinds of interaction, e.g. protein function, localization, structure, described in Gene Ontology or PDB.  The book discusses technologies, standards and databases for, respectively, generating, representing and storing PPI data. It also describes main algorithms and tools for the analysis, comparison and knowledge extraction from PINs. Moreover, some case studies and applications of PINs are also discussed'--
ER  -