Metabolism, pharmacokinetics, and toxicity of functional groups :  impact of the building blocks of medicinal chemistry in ADMET / 
edited by Dennis A. Smith 
 - Cambridge, [England] :  Royal Society of Chemistry,  2010 
 - xiv, 530 p. :  ill. ;  25 cm. 
 - RSC drug discovery series,  no. 1  2041-3203 ; .
<br/><br/>Drugs and their structural motifs -- ADMET for the medicinal chemist -- Carboxylic acids and their bioisosteres -- Primary, secondary, and tertiary amines and their isosteres -- Sulfonamide as an essential functional group in drug design -- Influence of aromatic rings on ADME properties of drugs -- Influence of heteroaromatic rings on ADME properties -- Peptidomimetics and peptides as drugs: motifs incorporated to enhance drug characteristics -- Pharmacokinetics and metabolism of compounds that mimic enzyme transition states -- Alcohols and phenols: absorption, distribution, metabolism, and excretion -- Future targets and chemistry and ADME needs 
<br/><br/><label>ISBN: </label>9781849730167 (hbk.)  RM680.44 1849730164 (hbk.) 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Pharmacokinetics<br/>Chemistry, Pharmaceutical--methods<br/>Pharmaceutical Preparations--metabolism
<br/><br/><label>National Library of Medicine Call No.: </label>QV38  / .M588 2010  9