TY - BOOK AU - Zhou,Xiaobo AU - Wong,Stephen T.C. TI - Computational systems bioinformatics: methods and biomedical applications SN - 9789812707048 (hardcover) PY - 2008/// CY - New Jersey PB - World Scientific KW - Computational Biology KW - methods KW - Microarray Analysis KW - Oligonucleotide Array Sequence Analysis KW - Statistics as Topic KW - method N1 - Includes bibliographical references and index; Mathematical, statistical, and data mining principles -- Missing value estimation using KNN and Bayesian methods -- Normalization, scaling, and discretization -- Cross-platform comparison -- Discovering differential biomarkers -- Gene selection and classification -- Gene clustering -- Gene prediction; Reverse engineering : gene regulatory network construction and its behavior -- Motif detection and transcription factor binding site (TFBS) identification -- Integrated microarray and gene sequence analysis -- Protein structure informatics -- Biomarker discovery from proteomics -- Bio-imaging informatics -- Conclusions ER -