Computational systems bioinformatics : methods and biomedical applications /
Xiaobo Zhou, Stephen T.C. Wong
- New Jersey : World Scientific, c2008
- x, 387 p. : ill. (some col.) ; 24 cm.
Includes bibliographical references and index.
Mathematical, statistical, and data mining principles -- Missing value estimation using KNN and Bayesian methods -- Normalization, scaling, and discretization -- Cross-platform comparison -- Discovering differential biomarkers -- Gene selection and classification -- Gene clustering -- Gene prediction Reverse engineering : gene regulatory network construction and its behavior -- Motif detection and transcription factor binding site (TFBS) identification -- Integrated microarray and gene sequence analysis -- Protein structure informatics -- Biomarker discovery from proteomics -- Bio-imaging informatics -- Conclusions