Walsh, Christopher <br/><br/>
Antibiotics :  actions, origins, resistance / 
by Christopher Walsh 
 - Washington :  ASM Press,  2003 
 - x, 335 p. :  ill. ;  26 cm. 
<br/><br/>References : p. 297-328 
<br/><br/>Antibiotics: initial concepts -- Introduction to major antibiotic classes and modes of action -- Antibiotics that act on cell wall biosynthesis -- Antibiotics that block bacterial protein biosynthesis -- Antibiotics that block DNA replication and repair: the quinolones -- Other targets of antibacterial drugs -- Natural and producer immunity versus acquired resistance -- Enzymatic destruction or modification of the antibiotic by resistant bacteria -- Antibiotic resistance by efflux pumps -- Antibiotic resistance by replacement or modification of the antibiotic target -- Regulation of antibiotic biosynthesis in producer organisms -- Polyketide antibiotic biosynthesis: assembly-line enzymology -- Enzymatic assembly lines for nonribosomal peptide antibiotics -- Biosynthesis of other classes of antibiotics -- New looks at targets -- New molecules -- Contexts and challenges for the use of new antibiotics 
<br/><br/><label>ISBN: </label>1555812546  RM401.80 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antibiotics--pharmacology<br/>Drug Resistance, Bacterial
<br/><br/><label>National Library of Medicine Call No.: </label>QV350