Genetic toxicology and cancer risk assessment - Choy, Wai Nang (New York : Marcel Dekker, 2001)
Human cancer genetics -- Genetic toxicity for predicting carcinogenicity -- Genotoxic and nongenotoxic mechanisms of carcinogenesis -- Structure-activity relationship (SAR) and its role in cancer risk assessment -- Regulatory genetic toxicology test -- Complementary genetic toxicology assays -- The mouse lymphoma assay (MLA) using the microwell method -- The in vivo micronucleus assay -- ICH guidances on genotoxicity and carcinogenicity : scientific background and regulatory practice -- New OECD genetic toxicity carcinogens -- Molecular epidemiology and biomarkers -- Quantitative cancer risk assessment of nongenotoxic carcinogens -- Risk assessment of genotoxic carcinogens -- Biologically based cancer risk assessment models
Includes bibliographical references and index
Keywords: Neoplasms -- etiology; Mutagenicity Tests -- methods; Risk Assessment