Validation of cell-based assays in the GLP setting : a practical guide / edited by Uma Prabhakar and Marian Kelley

Includes bibliographical references and index

Considerations while setting up cell-based assays / Marian Kelley -- Development, optimization and validation of cell based assays 1 / Marielena Mata and Thomas Lohr -- Development, optimization and validation of cell based assays 2 / Manjula Reddy and Uma Prabhakar -- Whole blood ex vivo stimulation assay development, optimization and validation / Manjula Reddy and Uma Prabhakar -- Immunohistochemistry assays in GLP studies / Frank Lynch ... [et al.] -- Flow cytometric cell based assays : an overview of general applications / Cuc Davis ... [et al.] -- T-cell surface markers in human peripheral whole blood using flow cytometry / Manjula Reddy ... [et al.] -- Intracellular cytokine detection by flow cytometry / Julie G. Wilkinson, Carlos A. Aparicio and Wade E. Bolton -- Validating reference samples for comparison in regulated ELISPOT assay / Magdalena Tary-Lehmann, Christina D. Hamm and Paul V. Lehmann -- IFN-[gamma] ELISPOT assay validation / Manjula Reddy ... [et al.] -- IL-5 ELISPOT assay validation / Manjula Reddy ... [et al.] -- Validation of the cylex technology to measure T and B cell activation capacity in clinical trials / Marielena Mata, Thomas Lohr and Jaymala Patel -- Development of validated neutralization bioassays / Manoj Rajadhyaksha ... [et al.] -- Endpoint assays in HIV-1 vaccine trials : functioning in a GLP environment / Patricia D'Souza ... [et al.] -- The future direction of cell-based assays / Uma Prabhakar and Marian Kelley