MARC details
| 000 -LEADER |
| fixed length control field |
02588cam a22003738i 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
| fixed length control field |
200603s2021 nju b 001 0 eng |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
| International Standard Book Number |
9783527347285 |
| Qualifying information |
(hardback) |
| Terms of availability |
RM616.25 (PTSL) |
| -- |
RM614.80 (PPUKM) |
| 040 ## - CATALOGING SOURCE |
| Original cataloging agency |
DLC |
| Language of cataloging |
eng |
| Description conventions |
rda |
| Transcribing agency |
DLC |
| Modifying agency |
UKM |
| Description conventions |
rda |
| 042 ## - AUTHENTICATION CODE |
| Authentication code |
pcc |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
QP551 |
| Local cutter number (OCLC) ; Book number/undivided call number, CALL (RLIN) |
.L643 |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
QP551 |
| Local cutter number (OCLC) ; Book number/undivided call number, CALL (RLIN) |
.L856 2021 9HUKM |
| 245 00 - TITLE STATEMENT |
| Title |
Long-lived proteins in human aging and disease / |
| Statement of responsibility, etc. |
edited by Roger Truscott. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
| Place of production, publication, distribution, manufacture |
Hoboken, NJ : |
| Name of producer, publisher, distributor, manufacturer |
Wiley, |
| Date of production, publication, distribution, manufacture, or copyright notice |
[2021] |
| 264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
| Date of production, publication, distribution, manufacture, or copyright notice |
©2021. |
| 300 ## - PHYSICAL DESCRIPTION |
| Extent |
x, 209 pages : |
| Other physical details |
illustrations ; |
| Dimensions |
25 cm. |
| 336 ## - CONTENT TYPE |
| Content type term |
text |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
| Media type term |
unmediated |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
| Carrier type term |
volume |
| Source |
rdacarrier |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
| Bibliography, etc. note |
Includes bibliographical references and index. |
| 520 ## - SUMMARY, ETC. |
| Summary, etc. |
'While most proteins in the human body are short-lived and are constantly being regenerated, this is not true for all. A significant fraction of proteins in long-lived cells such as nerve cells are likewise long-lived and will age over time by accumulating damage and other modifications. Scientists are only beginning to understand how this aging of long-lived proteins contributes to age-dependent diseases such as dementia and cancer Divided into six major sections, this comprehensive overview on an emerging topic in the molecular life sciences covers all aspects of the aging of (long-lived) proteins. Analytical methods to study protein half-life and the accumulation of modifications are presented, followed by several examples of long-lived proteins found in humans and other organisms. Next, the molecular mechanisms of aging on the protein level are described, in particular the most common side chain modifications, followed by a discussion of the consequences of protein aging on cellular and organ function. Finally, the impact of protein aging on several age-related disases in humans is dissected, and their role in limiting human lifespan is discussed'-- |
| Assigning source |
Provided by publisher. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name entry element |
Aging |
| General subdivision |
Molecular aspects. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name entry element |
Proteins. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name entry element |
Cells |
| General subdivision |
Aging. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name entry element |
Aging |
| General subdivision |
Physiological aspects. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
| Personal name |
Truscott, Roger J. W., |
| Relator term |
editor. |
| 907 ## - LOCAL DATA ELEMENT G, LDG (RLIN) |
| a |
.b16874961 |
| b |
2022-04-20 |
| c |
2021-08-30 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
| Koha item type |
AM |
| Suppress in OPAC |
No |
| Call number prefix |
QP551 .L643 |
| 949 ## - LOCAL PROCESSING INFORMATION (OCLC) |
| o |
101017441 |
| -- |
101012941 (PPUKM) |
| 990 ## - EQUIVALENCES OR CROSS-REFERENCES [LOCAL, CANADA] |
| Link information for 9XX fields |
ros/salmah/Rizal |
| 991 ## - LOCAL NOTE (NAMA FAKULTI/INSTITUT/PUSAT) |
| a |
INBIOSIS |
| 991 ## - LOCAL NOTE (NAMA FAKULTI/INSTITUT/PUSAT) |
| a |
Jabatan Perubatan, PPUKM. |
| 998 ## - LOCAL CONTROL INFORMATION (RLIN) |
| Library |
PERPUSTAKAAN TUN SERI LANANG |
| -- |
PERPUSTAKAAN PUSAT PERUBATAN UKM |
| Operator's initials, OID (RLIN) |
2021-08-30 |
| Cataloger's initials, CIN (RLIN) |
m |
| Material Type (Sierra) |
Printed Books |
| Language |
English |
| Country |
|
| -- |
0 |
| -- |
.b16874961 |