Protein therapeutics (Record no. 649078)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04677cam a2200661Ii 4500 |
| 001 - CONTROL NUMBER | |
| control field | ocn999588293 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250919141839.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS | |
| fixed length control field | m o d |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr |n||||||||| |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170804s2017 gw ob 001 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783527699131 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 3527699139 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783527699124 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 3527699120 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 3527340866 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 9783527340866 |
| 029 1# - OTHER SYSTEM CONTROL NUMBER (OCLC) | |
| OCLC library identifier | CHVBK |
| System control number | 495227986 |
| 029 1# - OTHER SYSTEM CONTROL NUMBER (OCLC) | |
| OCLC library identifier | CHNEW |
| System control number | 000964933 |
| 029 1# - OTHER SYSTEM CONTROL NUMBER (OCLC) | |
| OCLC library identifier | DEBSZ |
| System control number | 494212101 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)999588293 |
| Canceled/invalid control number | (OCoLC)998785567 |
| -- | (OCoLC)1000037842 |
| -- | (OCoLC)1002125199 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | YDX |
| Language of cataloging | eng |
| Transcribing agency | YDX |
| Modifying agency | NST |
| -- | IDEBK |
| -- | EBLCP |
| -- | NLE |
| -- | OCLCO |
| -- | DG1 |
| -- | OCLCQ |
| -- | NST |
| -- | RECBK |
| -- | OCLCF |
| -- | UAB |
| -- | UPM |
| -- | DEBSZ |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | MAIN |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RM666.P87 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 071000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 615.3 |
| Edition information | 23 |
| 245 00 - TITLE STATEMENT | |
| Title | Protein therapeutics |
| Medium | [electronic resource] / |
| Statement of responsibility, etc. | edited by Tristan Vaughan, Jane Osbourn, and Bahija Jallal. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Weinheim, Germany : |
| Name of publisher, distributor, etc. | Wiley-VCH, |
| Date of publication, distribution, etc. | [2017] |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 490 1# - SERIES STATEMENT | |
| Series statement | Methods and principles in medicinal chemistry ; |
| Volume/sequential designation | v. 71 |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Includes bibliographical references and index. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades. Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, all currently used therapeutic protein scaffolds are surveyed, from human and non-human antibodies to antibody mimetics, bispecific antibodies and antibody-drug conjugates. This ready reference then goes on to review other key aspects such as pharmacokinetics, safety and immunogenicity, manufacture, formulation and delivery. The handbook then takes a look at current key clinical applications for protein therapeutics, from respiratory and inflammation to oncology and immune-oncology, infectious diseases and rescue therapy. Finally, several exciting prospects for the future of protein therapeutics are highlighted and discussed. |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Cover ; Title Page ; Copyright ; Contents; Preface ; A Personal Foreword ; Acknowledgments ; Volume 1; Part I Introduction to Protein Therapeutics: Past and Present ; Chapter 1 Early Recombinant Protein Therapeutics ; 1.1 Introduction ; 1.2 The Birth of Genetic Engineering |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 1.3 Recombinant Human Insulin 1.3.1 The Race to Clone the Human Insulin Gene and to Produce Human Recombinant Insulin ; 1.3.2 Novo's Counter Strategy: Semisynthetic Human Insulin ; 1.3.3 Yeast Recombinant Insulin ; 1.4 Recombinant Human Growth Hormone ; 1.5 Recombinant Human Interferons |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 1.6 Recombinant Human Erythropoietin 1.7 Recombinant Tissue -- Type Plasminogen Activator ; 1.8 Recombinant Hepatitis B Virus (HBV) Vaccine ; 1.9 Postscript ; Acknowledgments ; References ; Chapter 2 Evolution of Antibody Therapeutics |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 2.1 Overview of Antibody Therapeutics Development 2.2 Polyclonal Antibodies -- Laying the Foundation for mAb Therapy ; 2.3 Evolution of Monoclonal Antibody Therapeutics ; 2.3.1 Chimeric and Humanized mAbs ; 2.3.2 Fully Human Antibodies ; 2.4 Fc Fusion Proteins |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 2.5 Evolution of Concepts in Antibody Pharmacology 2.5.1 Neutralization ; 2.5.2 From Killing Bacteria to Killing Human Cells ; 2.5.3 Targeting Membrane Receptors ; 2.6 Future Directions for Antibody Therapeutics Development ; Acknowledgments ; References |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein drugs. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Proteins |
| General subdivision | Therapeutic use. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | MEDICAL / Pharmacology |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein drugs. |
| Source of heading or term | fast |
| Authority record control number or standard number | (OCoLC)fst01079679 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Proteins |
| General subdivision | Therapeutic use. |
| Source of heading or term | fast |
| Authority record control number or standard number | (OCoLC)fst01079767 |
| 655 #4 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 655 #0 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Vaughan, Tristan, |
| Relator term | editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Osbourn, Jane, |
| Relator term | editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Jallal, Bahija, |
| Relator term | editor. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Qualifying information | Original |
| International Standard Book Number | 3527340866 |
| -- | 9783527340866 |
| Record control number | (OCoLC)988760633 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Methods and principles in medicinal chemistry ; |
| Volume/sequential designation | v. 71. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://eresourcesptsl.ukm.remotexs.co/user/login?url=https://doi.org/10.1002/9783527699124">https://eresourcesptsl.ukm.remotexs.co/user/login?url=https://doi.org/10.1002/9783527699124</a> |
| Public note | Wiley Online Library |
| 907 ## - LOCAL DATA ELEMENT G, LDG (RLIN) | |
| a | .b16816699 |
| b | 2022-11-02 |
| c | 2020-07-17 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Suppress in OPAC | No |
| 998 ## - LOCAL CONTROL INFORMATION (RLIN) | |
| Library | |
| Operator's initials, OID (RLIN) | 2020-07-17 |
| Cataloger's initials, CIN (RLIN) | m |
| Material Type (Sierra) | E-Book |
| Language | English |
| Country | |
| -- | 0 |
| -- | .b16816699 |
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